Yeah. Ones in the lower end of the plant and in the middle down there that never get direct light on them. Be selective and don't worry too much about whether to take or leave one as it really won't make a huge difference. Cannabis is very well suited to loosing parts of itself without causing any problems. Heavy defoliation is just such a waste in my opinion as the plant just turns it's energies to making more leaves rather than growing the whole plant. I mean they're the solar panels that power the plant and mother nature wouldn't grow them if they weren't critical to the plant's health.
If the plants are low on some nutrients they pull them from the older leaves so they also act as storage for times of need so you don't want to go crazy. The nodes draw a lot of energy to grow so like I said you can just nip them out and leave the leaves on if they are getting light. Now instead of feeding that node they help feed the whole plant. The plants have a circulatory system like we do so everything is always moving to where it's needed the most. It's a whole chemistry lab in there working 24/7 to make things work.