Blaze & Daze

Stiickygreen

Stiickygreen

Well-Known Member
curious2garden said:
Some people have very aggressive first pass systems and their liver cleans cannabinoids very efficiently which is why some people just don't get high off an edible. Add to the fact there is greater bioavailability via inhaled cannabinoids vs ingested (mode of administration in medications matter), some people don't get high off edibles.

It might be worth trying a larger dose to overwhelm the first pass efficiency but if you got a good liver I'm betting on the liver.
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Wow. Thanks for this. Always wondered >why<. Figured it was something like that/a different metabolism/etc/etc/etc. I'm also a dinosaur and don't react the same way others do to some drugs....like narcotics. They don't make me sleepy...they make me wanna party. Same gig when I go to the hospital and they try to knock me out. If it's just the nurse and her 2 syringes (dunno what it is)...LOL... let's just say I've amazed a few that I was still talking/functioning when they came back 10 minutes later....and I've had procedures done where I was far too present. Uggghh. I've seen vids that this may be due to weed and have had nurses say pretty much the same thing. It always takes the anesthesiologist to put me out fully. Your thoughts?

Back to cannabis:

As I say...I've tried many, many times over the years via my own edible concoctions and offerings from others as well. On my last attempt I de'carb'd and ate a gram of bubble hash baked into 2 cookies. I did get a mild effect...like I'd been in a car all day and was "still moving"... but it was something that I almost had to focus on to notice.

@ this point I've given up. No biggie. It would be nice to take away some of the jones to smoke though. (grabs bong) bongsmilie
 
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Dboybudz

Dboybudz

Well-Known Member
Stiickygreen said:
Wow. Thanks for this. Always wondered >why<. Figured it was something like that/a different metabolism/etc/etc/etc.

As I say...I've tried many, many times over the years via my own concoctions and offerings from others as well. On my last attempt I de'carb'd and ate a gram of bubble hash baked into 2 cookies. I did get a mild effect...like I'd been in a car all day and was "still moving"... but it was something that I almost had to focus on to notice.

@ this point I've given up. No biggie. It would be nice to take away some of the jones to smoke though. (grabs bong) bongsmilie
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Heck might try again never know and add lectin
Stiickygreen said:
Wow. Thanks for this. Always wondered >why<. Figured it was something like that/a different metabolism/etc/etc/etc.

As I say...I've tried many, many times over the years via my own concoctions and offerings from others as well. On my last attempt I de'carb'd and ate a gram of bubble hash baked into 2 cookies. I did get a mild effect...like I'd been in a car all day and was "still moving"... but it was something that I almost had to focus on to notice.

@ this point I've given up. No biggie. It would be nice to take away some of the jones to smoke though. (grabs bong) bongsmilie
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Might be worth to try again and add some lecithin to oil,or butter before cooking. I'm sure you already tried but never know ;)
 
Stiickygreen

Stiickygreen

Well-Known Member
Dboybudz said:
Heck might try again never know and add lectin

Might be worth to try again and add some lecithin to oil,or butter before cooking. I'm sure you already tried but never know ;)
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BT, DT. :rolleyes: Besides a liver transplant...seems like I'm on the outs. I'm not really interested in taking 500mg and up for an effect.

I'd rather just smoke the hash and eat the cookies later...though I do enjoy the taste of a good cannabis cookie/brownie and have munched heavily on people's "treats"...much to their disdain. :p
 
raratt

raratt

Well-Known Member
curious2garden said:
Some people have very aggressive first pass systems and their liver cleans cannabinoids very efficiently which is why some people just don't get high off an edible. Add to the fact there is greater bioavailability via inhaled cannabinoids vs ingested (mode of administration in medications matter), some people don't get high off edibles.

It might be worth trying a larger dose to overwhelm the first pass efficiency but if you got a good liver I'm betting on the liver.

Here's the actual science for you (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803256/):
After THC is absorbed, it travels to the liver where most of it is eliminated or metabolized to 11-OH-THC or 11-COOH-THC. The remaining THC and its metabolites enter the circulation. The bioavailability of ingested THC is only 4% to 12%. THC is highly lipid soluble and is therefore rapidly taken up by fat tissue. The plasma half-life of THC is 1 to 3 days in occasional users and 5 to 13 days in chronic users. The bioavailability of CBD via inhalation is 11% to 45%, whereas that of oral CBD is 6%. CBD has high lipophilicity and therefore is rapidly distributed in the brain, adipose tissue, and other organs. CBD is hydroxylated to 7-OH-CBD and 7-COOH-CBD by cytochrome P450 enzymes CYP3A4 and CYP2C9 in the liver and is excreted mainly in feces and less in urine. The plasma half-life of CBD is 18 to 32 hours.
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Exactly. :shock:
Mornin.
I need more coffee.
 
wakeNbaker46

wakeNbaker46

Well-Known Member
sunny sunday indeed, around here! 55 and not a cloud in sight. just mixed up the newest batch of auto medium, and transplanted the three mephisto SODK x skystomper 2.0's.
PXL_20240324_164232554.jpg
they got the same, but different, mix as the last two auto runs: FFHF, perlite, ewc, Dr Earth dry amendments. this time i added FFOF as well, and the recycled medium from the greenpoint Oreoz bag since i chopped that this morning. not a white hair in sight, cloudy trichomes, and i want the space back in the tent :lol:
PXL_20240324_165512084.jpg
i did more defoliation with this second run, and ended up with 7 colas that all pretty much look the same in size and girth. gonna do a little wet trimming this evening and pop everything in the walk-in. i'm pretty happy so far with the greenpoint girls; smoke report to come in the coming weeks, of course.
first two auto runs have been in 3G pots. these new girls are ini 7G. might be overkill, but based on the roots that were coming out of the 3G pot, i think they'll be happy with more room.
PXL_20240324_164102906.jpg
the chernobyl babes are hanging out with their marigold and zinnia cousins for at least another week. my plan is to mix up a Build A Soil batch from scratch and put those in 3G (eventually 10G) pots in the tent, at which point the 3 mephistos and the 2 chernobyls will all have to "make it work" (an old saying of my dad's when the four kids were bickering about something stupid) within the 4x4. ideally the weather warms up and i can move the autos outdoors, transplant the photos into their 10G pots, fill up the 4x4 and cross my fingers that 2 mediums + 2 environments + 3 strains doesn't = madness and failure.
PXL_20240324_164342490.jpg
 
Dboybudz

Dboybudz

Well-Known Member
wakeNbaker46 said:
sunny sunday indeed, around here! 55 and not a cloud in sight. just mixed up the newest batch of auto medium, and transplanted the three mephisto SODK x skystomper 2.0's.
View attachment 5380615
they got the same, but different, mix as the last two auto runs: FFHF, perlite, ewc, Dr Earth dry amendments. this time i added FFOF as well, and the recycled medium from the greenpoint Oreoz bag since i chopped that this morning. not a white hair in sight, cloudy trichomes, and i want the space back in the tent :lol:
View attachment 5380617
i did more defoliation with this second run, and ended up with 7 colas that all pretty much look the same in size and girth. gonna do a little wet trimming this evening and pop everything in the walk-in. i'm pretty happy so far with the greenpoint girls; smoke report to come in the coming weeks, of course.
first two auto runs have been in 3G pots. these new girls are ini 7G. might be overkill, but based on the roots that were coming out of the 3G pot, i think they'll be happy with more room.
View attachment 5380613
the chernobyl babes are hanging out with their marigold and zinnia cousins for at least another week. my plan is to mix up a Build A Soil batch from scratch and put those in 3G (eventually 10G) pots in the tent, at which point the 3 mephistos and the 2 chernobyls will all have to "make it work" (an old saying of my dad's when the four kids were bickering about something stupid) within the 4x4. ideally the weather warms up and i can move the autos outdoors, transplant the photos into their 10G pots, fill up the 4x4 and cross my fingers that 2 mediums + 2 environments + 3 strains doesn't = madness and failure.
View attachment 5380616
Click to expand...
You clearly got this down everything looks awesome, really sweet for them autos, everyone I've heard said 3 gallon for auto maybe 5 if already planted then leave em. I never tried autos so your good experience with them are great, looking forward to smoke report :D
 
tyler.durden

tyler.durden

Well-Known Member
wakeNbaker46 said:
sunny sunday indeed, around here! 55 and not a cloud in sight. just mixed up the newest batch of auto medium, and transplanted the three mephisto SODK x skystomper 2.0's.
View attachment 5380615
they got the same, but different, mix as the last two auto runs: FFHF, perlite, ewc, Dr Earth dry amendments. this time i added FFOF as well, and the recycled medium from the greenpoint Oreoz bag since i chopped that this morning. not a white hair in sight, cloudy trichomes, and i want the space back in the tent :lol:
View attachment 5380617
i did more defoliation with this second run, and ended up with 7 colas that all pretty much look the same in size and girth. gonna do a little wet trimming this evening and pop everything in the walk-in. i'm pretty happy so far with the greenpoint girls; smoke report to come in the coming weeks, of course.
first two auto runs have been in 3G pots. these new girls are ini 7G. might be overkill, but based on the roots that were coming out of the 3G pot, i think they'll be happy with more room.
View attachment 5380613
the chernobyl babes are hanging out with their marigold and zinnia cousins for at least another week. my plan is to mix up a Build A Soil batch from scratch and put those in 3G (eventually 10G) pots in the tent, at which point the 3 mephistos and the 2 chernobyls will all have to "make it work" (an old saying of my dad's when the four kids were bickering about something stupid) within the 4x4. ideally the weather warms up and i can move the autos outdoors, transplant the photos into their 10G pots, fill up the 4x4 and cross my fingers that 2 mediums + 2 environments + 3 strains doesn't = madness and failure.
View attachment 5380616
Click to expand...
Nice job. That Oreoz looks tasty. I'm cloning some cuttings of her now, I've got 2 going in next run. Please let us know how she smokes, my clones promised 32% THC and chocolate undertones. Yummy.
 
wakeNbaker46

wakeNbaker46

Well-Known Member
curious2garden

curious2garden

Well-Known Mod
Staff member
FirstCavApache64

FirstCavApache64

Well-Known Member
curious2garden said:
That's gorgeous. Then I thought how bad would he smack me if I said two more weeks :lol:
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It has a few white pistils because I cranked the light in weeks 7 and 8 and it popped new pistils on all the tops but it's falling over every day from the swelling in the last couple weeks as it packed on density. I don't check trichomes but I'd say there's a good bit of amber showing most likely. The Wedding Cake it's next to is tired of getting smooshed when it falls over so it's time. Wedding Cake is another one I'm really liking.
20240324_151315.jpg
20240324_151257.jpg
 
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