weed makin u feel wierd

[palmtree]

psycologists call that a locked in stage, basically if you have smoked regularly and daily for a sustained amount of time your brain adapts to the intoxication and begins to operate in that state. conversly once lock in has begun the individual will begin to feel more "normal" during their high and less in control and alert during the sober moment.
Lock in stage is not a good thing and it can go away with prolonged sobriety with the time line of a cleaning procccess directly connected to the severity of your lock in stage.

interestingly, this caused by the same receptors that are stimulated through tripping (its why MJ is considered a hallusinigenic) and hard tripp do the same thing on a much more sever level.. and that where flash backs and acid head cases most commonly come from..

good luck

LOL that would freak me out if I was as high as UKgrower2011

 

[shepj]

cannabis is not a drug, it is plant matter that contains drugs

Then the opium poppy isn't a drug, coca plants isn't a drug, mescaline containing cacti aren't drugs, and psilocybe mushrooms aren't drugs..

c'mon.. pot is a fucking drug.

sorry but that reply is total bs.

not only is that locked in stage some prohibitionist bs, but so is your crap on the receptors.

Actually you are incorrect. It is not really "locked in stage" but it is similar, your mind gets accustomed to doing things under the influence of certain substances and we develop what is known as "State Dependent Learning".

EDIT:

no it doesn't happen to me at all.

the reason cannabis can't turn us into permanent zombies, or damage our system in any way, is because the cannabinoid receptors protect our body from any over-reaction by down-regulation (turning off excess receptors when it's over-exposed.)

other drugs don't have such a receptor to act on, so they wreak havoc on our system in high doses.

the science does matter, otherwise you're an idiot believing misinformation.

Do you know anything about neuropharmacology or do you just talk shit to hear yourself talk?

We have pcp receptors, µ-opioid receptors, cannabinoid receptors, and various other receptors that drugs hit on (for instance tryptamines play off of the serotonin receptor, and other drugs play with a combination of norepinephrine/epinephrine, dopamine, and serotonin receptors).

Explain to me.. we have µ-opioid receptors (as in receptors meant to activate Opiates/Opioids), why don't these receptors "protect our body from any over-reaction"?

Oh yeah that's right, because you got the word receptor fucked up with enzyme you dick.

 

[GrowSpecialist]

 

[pinstash]

an old friend of mine has parents that are still locked in the 70's,lol, but they are great people, and its nice to go over and see them every so often, i get to experience an era i was born in lol.

 

[HoLE]

does weed make u feel weird, i feel like everything doesnt exist, really zoned out, is this normal? does it happen to u guys aswell?

if I'm at work,,it put's me in a zone,totally energized and peakin,,if I'm at home,,or not working,,I'm in a different zone,more like I'm relaxed and baked,,and don't give a fuck,,when you are in control of your habits,,it's easy to make the best of a 6 pack,an a half a quarter,,,or a 2-4 and a ounce

 

[HoLE]

if I'm at work,,it put's me in a zone,totally energized and peakin,,if I'm at home,,or not working,,I'm in a different zone,more like I'm relaxed and baked,,and don't give a fuck,,when you are in control of your habits,,it's easy to make the best of a 6 pack,an a half a quarter,,,or a 2-4 and a ounce

hey,,,,that should be some new iconic saying,,,,,,Make the Best of a 6 pack and a half quarter,,,,Unless You Got a 24 and an Ounce!!!

 

[poplars]

Then the opium poppy isn't a drug, coca plants isn't a drug, mescaline containing cacti aren't drugs, and psilocybe mushrooms aren't drugs..

c'mon.. pot is a fucking drug.



Actually you are incorrect. It is not really "locked in stage" but it is similar, your mind gets accustomed to doing things under the influence of certain substances and we develop what is known as "State Dependent Learning".

EDIT:



Do you know anything about neuropharmacology or do you just talk shit to hear yourself talk?

We have pcp receptors, µ-opioid receptors, cannabinoid receptors, and various other receptors that drugs hit on (for instance tryptamines play off of the serotonin receptor, and other drugs play with a combination of norepinephrine/epinephrine, dopamine, and serotonin receptors).

Explain to me.. we have µ-opioid receptors (as in receptors meant to activate Opiates/Opioids), why don't these receptors "protect our body from any over-reaction"?

Oh yeah that's right, because you got the word receptor fucked up with enzyme you dick.

ok well let me correct myself on this one, I agree we do have ligand receptors such as opioid receptors and all that.

but the cannabinoid receptors seem to be arranged in our system to caused the least amount of damage. and they also seem to down-regulate much faster than opioid receptors.

or perhaps it's all based on the placement of the receptors in our nervous system and other parts of our body.

either way, thanks for calling me a dick, dick.

 

[HoLE]

ok well let me correct myself on this one, I agree we do have ligand receptors such as opioid receptors and all that.

but the cannabinoid receptors seem to be arranged in our system to caused the least amount of damage. and they also seem to down-regulate much faster than opioid receptors.

or perhaps it's all based on the placement of the receptors in our nervous system and other parts of our body.

either way, thanks for calling me a dick, dick.

don't ya just hate when that happens

 

[shepj]

but the cannabinoid receptors seem to be arranged in our system to caused the least amount of damage. and they also seem to down-regulate much faster than opioid receptors.

or perhaps it's all based on the placement of the receptors in our nervous system and other parts of our body.

You do realize that it is enzymes that break down chemicals, no?

For instance:

Dextromethorphan (DXM) -via CYP2D6 Enzyme- > Dextrorphan (DXO)

The CYP2D6 enzyme is responsible for the demethylation that takes place in the body.

and one more thing, cannabis is classified as a sedative hypnotic, NOT a hallucinogen.

THC is a psychedelic and is hallucinogenic at 0.4 to 0.5 mg./kg

 

[cerberus]

no it doesn't happen to me at all.

the reason cannabis can't turn us into permanent zombies, or damage our system in any way, is because the cannabinoid receptors protect our body from any over-reaction by down-regulation (turning off excess receptors when it's over-exposed.)

and that physiologicval responce is due to and over load and over stimulation. this burned in stage is also known as lock in stage.

propaganda does exisists and there are a lot of lies out there but just because it stands against your convienice doesnt mean it is a lie.

secondly nobody said it was perminant, it just means you need to take a break and let your head get accliamitized to not being high again.

this is also akin to why we hit ceilings and tolerance to certain weed.

other drugs don't have such a receptor to act on, so they wreak havoc on our system in high doses.

the science does matter, otherwise you're an idiot believing misinformation.

receptor is a generic word.. it defines the acts of accepting information or stimulous..

misinformation..

 

[cerberus]

Then the opium poppy isn't a drug, coca plants isn't a drug, mescaline containing cacti aren't drugs, and psilocybe mushrooms aren't drugs..

c'mon.. pot is a fucking drug.



Actually you are incorrect. It is not really "locked in stage" but it is similar, your mind gets accustomed to doing things under the influence of certain substances and we develop what is known as "State Dependent Learning".

EDIT:



Do you know anything about neuropharmacology or do you just talk shit to hear yourself talk?

We have pcp receptors, µ-opioid receptors, cannabinoid receptors, and various other receptors that drugs hit on (for instance tryptamines play off of the serotonin receptor, and other drugs play with a combination of norepinephrine/epinephrine, dopamine, and serotonin receptors).

Explain to me.. we have µ-opioid receptors (as in receptors meant to activate Opiates/Opioids), why don't these receptors "protect our body from any over-reaction"?

Oh yeah that's right, because you got the word receptor fucked up with enzyme you dick.

10.4 I agree with all of this..

 

[cerberus]

ok well let me correct myself on this one, I agree we do have ligand receptors such as opioid receptors and all that.

but the cannabinoid receptors seem to be arranged in our system to caused the least amount of damage. and they also seem to down-regulate much faster than opioid receptors.

or perhaps it's all based on the placement of the receptors in our nervous system and other parts of our body.

either way, thanks for calling me a dick, dick.

these words are subjective describers..

calling you a dick SEEEMS more objective..