I would have to take the other side of the coin on that statement. LSD will always be the new LSD. But from your stance of reclaiming the title of most usable, beneficial and easily accessible, correct? I would have to agree with one of the 2c's for sure, but from what I have read, i is more visual, while e is more empatheogenic.
While not having tried e, I would have to say e is the new e(MDMA). Where as i, is the new LSD. But there are many other candidates I haven't tried or am not even familiar with.
I really wish some lysergic analogs hit the RC market in the near future.
Peace