Robby648: not knowing what nutes you're using I can only say, yes, it can and will change and some times very rapidly depending on the growth stage of your plants and how heavily they're feeding, but they should be good for 24 hours. A trusted friend of mine gave me some good advice starting out and I'll pass it on to you. If you're growing my favorite herb and you're using a good brand of nutes correctly, he said, "Check and adjust your nutes to 5.8. Recheck and readjust it back to 5.8 at about the same time everyday and don't worry about it as long as your plants look healthy." He also added, "Keep your garden clean." HSA