i would not risk it that early into flowering, i would remove them and buy x4 fem seeds, 12/12 from seed to compensate for you're loss. And from what i have heard big bud is a strain known for this type of behavior, but yeah, i would ditch them and find some new strains to compensate, you can go to attitude seed bank and pick 1 seed of different strains, fem seeds aswell. i would go there and have a look for some replacements, as you just lost half of you're final outcome, x4 new seeds, because theywill be pretty small but should be able to compensate for ur loss (Put them in small pots remember, you wont have enough space for the 2 you have and 4 more in massive pots, 5L pots should be more than enough im gonna be using 1L airpots for 12/12 from seed/clone).