I've been using trams for about 5 years,I take 450mgs every day for back & neck issues,opiates do nothing for me so trams is the only choice I have,doctors dropped me and came up dirty for weed so they shut me down on my trams,I said fuck you doc I'll get em online,found a guy that sells 150mg capsules for $1 each just to help people that can't afford medical help,thats 3 caps a day for a great price compared to other online pharmacies,this guy will let ya order as many as you want but I only need 100 a month as I don't abuse,they can have serious side affects in long term use and for some people high doses can cause serious seizures or death,chance I have to take because without them I have no quality of life even with me weed at my side.