defoliation during veg is a definate no no, but i have seen some evidence that removal of old fan leaves half way through the flowering cycle can increase yield, however i cant say from experience if it actually works. the theory behind it is that the old veg leaves are no longer feeding bud growth as that job is being fulfilled by the new sugar leaves that grow as the bud develops and that the large fan leaves end up using more energy to maintain themselves then they produce. I have been reluctant to try it though as i only do small 4-5 plant grows usually from seed so any difference in yield could be because of different phenotypes. but i cant deny the evidence ive seen has made me want to give it a try and ill likely give i a shot on my next clone only grow, but that is still several months away as im currently auditioing for a new mother plant