My minimal experience, that is fine for one plant, until it gets so tall that not all the light hits it. Then you need to add another light just to reach it all. But in general, 1 small plant seems fine with 1 42w CFL as long all areas are getting light. Again, this is for a small plant. EDIT: I used 3 CFLs on a 4 ft" tall plant, but 1 CFL might sustain one of those 12/12 1oz grows.