I inspect my primary colas for budrot throughout flower, all the way through to trimming, and I just cut it out when I see it. When I see it in flower, I make sure I cut out enough, and I'm sure I waste good bud in the process. When I see it while drying/curing, I usually just toss that bud and move on, I don't alter anything else. Since I'm always looking for it, I end up not losing much of my yield overall. I do regular IPM through veg, and I keep a hepa filter running in my lung room-I think those are the best prevention for the average grower. The reactive oxygen generators work very well for commercial growers, but you don't want one in your bedroom!