Just wanted to chime in on this. I've been smoking for about 20 years and maybe 3 years ago I started getting anxiety and panic attacks from smoking. I legit went to the hospital the first time cause I thought I was having a heart attack. They gave me an EKG and all the usual checkups and turned out I was fine. Didn't feel like it though. I didn't associate it with the weed that first time, didn't even think to mention it, I saw no connection.
Maybe a week later I had another episode, and I tried to smoke to reduce the anxiety (that's how it always worked for me prior to this) and ended up sending myself into another full-blown panic attack. Back to the hospital I went, and this time they asked if I had smoked weed. I told them yes and almost laughed it off when they told me it was probably the cause of the panic attacks.
Anyway, here we are 3 years later and I still get them. I was a pretty heavy smoker/dabber before this all happened. Maybe a few grams of flower and a half a gram of good concentrates on a regular day realistically smoked 3-4 joints a day plus dabs. Out of nowhere, I couldn't take a few puffs without having a major reaction.
I was sent to a cardiologist by referral, the guy turns out to be a Phish fan. Tells me I can smoke weed, eat LSD or shrooms, but not coke and no dope. "If you get anxiety or have a panic attack, it's your fault. It's not going to kill you though." That's basically what he said. lol. I got a good kick out of that. He told me my anxiety was the result of losing my pops, my dog died and I my daughter was born all within a 6 month period. It was a grueling part of my life, so much was going on.. apparently "big life changes" can cause this anxiety to creep up inside of you. Still not sure what I believe. There were a few months where I couldn't smoke at all, just 2-3 puffs sent me into a downward spiral, especially if I choked. Needless to say, I went for almost 3 months with no smoking at all.
I've also been in the worst physical shape of my life, 40 lbs heavier than my heavest before I turned 30. I weigh 220, always used to be 170-180. Once I hurt my back I put on a bunch of weight, didn't leave the couch for like 2-3 months, it was bad. So half of me believes that has something to do with it as well. Currently working on better dieting and exercise, but it ain't easy! Gotta get my bp down a cpl and lose this belly haha.
So, now I smoke a little here and there. I am trying to get into growing now as well, I just love the plant. Whenever I smoke I just take a few puffs and give it a minute... you can usually feel the anxiety come on pretty early, it's pretty physical for me, not so much mental. If I feel anything of the sort I will tap out, but some days I can smoke a few joints and I am fine.
Some people say to smoke through it... that feels impossible because I have this whole new idea of mortality since having a child. When I get those panic attacks I feel like I'm gonna drop dead. I know I'm not, but it sure as hell feels like it. lol. That's a hard thing to smoke through.
There is one plus side to all this... the amount of money saved. lol.
Sidenote: It isn't strain-dependent, it seems to be totally random. Indica, sativa, hybrid, you name it. I've even tried strains that people say are meant for anxiety. Still happens. Sometimes I can smoke one strain one day, and not the next. CBD does nothing to help. Sometimes I can do dabs and it gives me LESS anxiety than when I smoke flower. There was a period when I could dab but not burn a j. Shit's so weird and random. I really wish I could be part of some sort of study. Hopefully, they research things like this with legalization being a thing in so many states. From our own research, a friend of mine and myself have come to the conclusion that I either broke my cannabinoid system from long term overuse, or your system works kind of like your tastebuds, and after so many years it redirects THC to different receptors in the brain/body.