Pandemic 2020

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DIY-HP-LED

Well-Known Member
Good luck with treatment in LA, maybe Donald will send him some antibodies, this might be bye, bye Larry.
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Larry King hospitalized with COVID-19 (pagesix.com)

Larry King hospitalized with COVID-19

Veteran talk show host Larry King has been hospitalized in Los Angeles with COVID-19.

The 87-year-old broadcasting legend has survived multiple health scares in the past, including a heart attack, a stroke, prostate and lung cancer and diabetes.

He spent his 87th birthday, in November, hospitalized with a blood-flow issue.

The former CNN powerhouse has been ill for 10 days, Roger Friedman’s Showbiz 411 reported.

Neither King’s wife, Shawn, or their two sons, Chance and Cannon, can visit him in the hospital. The couple is in the process of divorcing but is said to be on good terms, the Daily Mail reported.

King also has an older son, Larry Jr. Two of his children died in 2020: Andy, 65, from a heart attack and Chaia, 51, from lung cancer.
 

DIY-HP-LED

Well-Known Member
Off topic, but health related and of importance to many members.
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Drug Reverses Age-Related Mental Decline Within Days | UC San Francisco (ucsf.edu)

Drug Reverses Age-Related Mental Decline Within Days
Rapid Rejuvenation of Mental Faculties in Aged Mice Implicates Reversible Physiological ‘Blockage’ Behind Age-Related Cognitive Losses

Just a few doses of an experimental drug can reverse age-related declines in memory and mental flexibility in mice, according to a new study by UC San Francisco scientists. The drug, called ISRIB, has already been shown in laboratory studies to restore memory function months after traumatic brain injury (TBI), reverse cognitive impairments in Down Syndrome, prevent noise-related hearing loss, fight certain types of prostate cancer, and even enhance cognition in healthy animals.

In the new study, published Dec. 1, 2020, in the open-access journal eLife, researchers showed rapid restoration of youthful cognitive abilities in aged mice, accompanied by a rejuvenation of brain and immune cells that could help explain improvements in brain function.

“ISRIB’s extremely rapid effects show for the first time that a significant component of age-related cognitive losses may be caused by a kind of reversible physiological “blockage” rather than more permanent degradation,” said Susanna Rosi, PhD, Lewis and Ruth Cozen Chair II and professor in the departments of Neurological Surgery and of Physical Therapy and Rehabilitation Science.

“The data suggest that the aged brain has not permanently lost essential cognitive capacities, as was commonly assumed, but rather that these cognitive resources are still there but have been somehow blocked, trapped by a vicious cycle of cellular stress,” added Peter Walter, PhD, a professor in the UCSF Department of Biochemistry and Biophysics and a Howard Hughes Medical Institute investigator. “Our work with ISRIB demonstrates a way to break that cycle and restore cognitive abilities that had become walled off over time.”

Could Rebooting Cellular Protein Production Hold the Key to Aging and Other Diseases?
Walter has won numerous scientific awards, including the Breakthrough, Lasker and Shaw prizes, for his decades-long studies of cellular stress responses. ISRIB, discovered in 2013 in Walter’s lab, works by rebooting cells' protein production machinery after it gets throttled by one of these stress responses – a cellular quality control mechanism called the integrated stress response (ISR; ISRIB stands for ISR InhiBitor).

The ISR normally detects problems with protein production in a cell — a potential sign of viral infection or cancer-promoting gene mutations — and responds by putting the brakes on cell’s protein-synthesis machinery. This safety mechanism is critical for weeding out misbehaving cells, but if stuck in the on position in a tissue like the brain, it can lead to serious problems, as cells lose the ability to perform their normal activities, Walter and colleagues have found.

In particular, recent animal studies by Walter and Rosi, made possible by early philanthropic support from The Rogers Family Foundation, have implicated chronic ISR activation in the persistent cognitive and behavioral deficits seen in patients after TBI, by showing that, in mice, brief ISRIB treatment can reboot the ISR and restore normal brain function almost overnight.

The cognitive deficits in TBI patients are often likened to premature aging, which led Rosi and Walter to wonder if the ISR could also underlie purely age-related cognitive decline. Aging is well known to compromise cellular protein production across the body, as life’s many insults pile up and stressors like chronic inflammation wear away at cells, potentially leading to widespread activation of the ISR.

“We’ve seen how ISRIB restores cognition in animals with traumatic brain injury, which in many ways is like a sped-up version of age-related cognitive decline,” said Rosi, who is director of neurocognitive research in the UCSF Brain and Spinal Injury Center and a member of the UCSF Weill Institute for Neurosciences. “It may seem like a crazy idea, but asking whether the drug could reverse symptoms of aging itself was just a logical next step.”

Improves Cognition, Boosts Neuron and Immune Cell Function
In the new study, researchers led by Rosi lab postdoc Karen Krukowski, PhD, trained aged animals to escape from a watery maze by finding a hidden platform, a task that is typically hard for older animals to learn. But animals who received small daily doses of ISRIB during the three-day training process were able to accomplish the task as well as youthful mice, much better than animals of the same age who didn’t receive the drug.

The researchers then tested how long this cognitive rejuvenation lasted and whether it could generalize to other cognitive skills. Several weeks after the initial ISRIB treatment, they trained the same mice to find their way out of a maze whose exit changed daily – a test of mental flexibility for aged mice who, like humans, tend to get increasingly stuck in their ways. The mice who had received brief ISRIB treatment three weeks before still performed at youthful levels, while untreated mice continued to struggle.

To understand how ISRIB might be improving brain function, the researchers studied the activity and anatomy of cells in the hippocampus, a brain region with a key role in learning and memory, just one day after giving animals a single dose of ISRIB. They found that common signatures of neuronal aging disappeared literally overnight: neurons' electrical activity became more sprightly and responsive to stimulation, and cells showed more robust connectivity with cells around them while also showing an ability to form stable connections with one another usually only seen in younger mice.

The researchers are continuing to study exactly how the ISR disrupts cognition in aging and other conditions and to understand how long ISRIB’s cognitive benefits may last. Among other puzzles raised by the new findings is the discovery that ISRIB also alters the function of the immune system’s T cells, which also are prone to age-related dysfunction. The findings suggest another path by which the drug could be improving cognition in aged animals, and could have implications for diseases from Alzheimer’s to diabetes that have been linked to heightened inflammation caused by an aging immune system.

“This was very exciting to me because we know that aging has a profound and persistent effect on T cells and that these changes can affect brain function in the hippocampus,” said Rosi. “At the moment, this is just an interesting observation, but it gives us a very exciting set of biological puzzles to solve.”
 

DIY-HP-LED

Well-Known Member
Broad Effects Exemplify ‘Serendipity’ of Basic Research
Rosi and Walter were introduced by neuroscientist Regis Kelly, PhD, executive director of the University of California’s QB3 biotech innovation hub, following Walter’s 2013 study showing that the drug seemed to instantly enhance cognitive abilities in healthy mice. To Rosi, the results from that study implied some walled-off cognitive potential in the brain that the molecule was somehow unlocking, and she wondered if this extra cognitive boost might benefit patients with neurological damage from traumatic brain injury.

The labs joined forces to study the question in mice, and were astounded by what they found. ISRIB didn’t just make up for some of the cognitive deficits in mice with traumatic brain injury – it erased them. “This had never been seen before,” Rosi said. “The mantra in the field was that brain damage is permanent – irreversible. How could a single treatment with a small molecule make them disappear overnight?”

Further studies demonstrated that neurons throughout the brains of animals with traumatic brain injury are thoroughly jammed up by the ISR. Using ISRIB to release those brakes lets brain cells immediately get back to their normal business. More recently, studies in animals with very mild repetitive brain injury – akin to pro athletes who experience many mild concussions over many years – showed that ISRIB could reverse increased risk-taking behavior associated with damage to self-control circuits in the frontal cortex.

“Added to this, Karen’s new results in aging mice are just amazing. It’s not often that you find a drug candidate that shows so much potential and promise,” Walter added. “This project also shows the power of the UCSF community – Susanna and I didn’t know each other and were living in different worlds until Regis Kelly brought us together, making this powerful connection that neither of us had realized before.”

“Amazing breakthroughs like this need more than the brilliance and experimental skills of Susanna and Peter,” said Kelly. “They also need donors like the Rogers Family Foundation willing to bridge the gap between great basic research and products that could be highly beneficial to society.”

ISRIB has been licensed by Calico, a South San Francisco, Calif. company exploring the biology of aging, and the idea of targeting the ISR to treat disease has been picked up by many other pharmaceutical companies, Walter says.

One might think that interfering with the ISR, a critical cellular safety mechanism, would be sure to have serious side effects, but so far in all their studies, the researchers have observed none. This is likely due to two factors, Walter says. First, it takes just a few doses of ISRIB to reset unhealthy, chronic ISR activation back to a healthier state, after which it can still respond normally to problems in individual cells. Second, ISRIB has virtually no effect when applied to cells actively employing the ISR in its most powerful form – against an aggressive viral infection, for example.

Naturally, both of these factors make the molecule much less likely to have negative side effects – and more attractive as a potential therapeutic. “It almost seems too good to be true, but with ISRIB we seem to have hit a sweet spot for manipulating the ISR with an ideal therapeutic window,” Walter said.
 

DIY-HP-LED

Well-Known Member
We don't like no big guberment and we don't like no stink'n masks, FREEDOM! Yep if this hits North America they will be breaking up anti mask rallies with flamethrowers. Not just in the states either, this UK strain alone might lead to four times the deaths and hospitalizations, hospitals are near capacity and exceeding it in many places. If the new SA strain is vaccine resistant and just as contagious we are fucked, with overloaded hospitals, exhausted staffs and skyrocketing death rates. A large percentage of the 20% of people who normally would end up in hospital would probably die, mortality could be as high as 10% in the untreated.

Once these strains are let loose in the USA it will be a nightmare and not much better in Canada, if the SA variant is vaccine resistant it will be a catastrophe of mass death. There will be very little tolerance of anti maskers and "fakenews" types, things will get very ugly very quickly for them, if the threat level increases dramatically. This is gonna end up as a race of vaccination rates against new variant infection rates. We had better hope the new SA variant if not resistant to the existing vaccines or things could get ugly real fucking fast. If the vaccines won't work with the new strain, neither will the immunity of those who were infected with older strains of covid.
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Britain’s Mutant Coronavirus Strain Has Swamped the Nation, But a Worse Variant Has Already Arrived

GOING UNDER
The daily rate of cases has more than tripled in little over a month and the measures that worked last year are simply not enough this time round.


EDINBURGH, Scotland—It’s only been a few weeks since people in Britain were planning a relatively normal Christmas time with their families thanks to relaxed pandemic rules. Now, with the mutant coronavirus variant fuelling a near-vertical spike in new daily cases, huge parts of the country are starting the new year by being slammed back into the harshest of lockdowns.

The speed of the turnaround has been astonishing and terrifying. At the end of November, following a nationwide lockdown in England, Britain’s case numbers had declined to around 13,000 a day. Now the country has recorded more than 50,000 cases for six days in a row.

By way of comparison, England has recorded 476.9 cases per 100,000 people in the past week—a rate nearly five times worse than California, the worst-affected U.S. state, which, according to the U.S. Centers for Disease Control and Prevention, is recording 98.8 cases per 100,000. The message to the world appears to be clear—the new variant spreads faster, and, without strict preventative measures, this will happen to you too.

1609787541186.png

Britain’s surge comes despite the planned Christmas relaxation being scrapped, schools closing down for Christmas, and the biggest city, London, being in the top-tier of lockdown for two weeks. Experts have been warning for weeks that the new variant spreads so quickly that rules that may have been worked last year are no longer enough. Political leaders are now scrambling to find how to knock it back, or face catastrophe.

Scotland has gone first. Its devolved nationalist government had already closed the border to England after Prime Minister Boris Johnson confirmed that the new variant was running wild down south. On Monday, Scotland’s first minister, Nicola Sturgeon, announced a lockdown every bit as strict as the one in spring. Her message—stay at home, and keep your kids out of school, or we’ll end up as screwed as England.

Sturgeon has estimated that Scotland is now about four weeks behind England’s surge, but the new rules—which force Scots by law not to leave their homes but for a few essential purposes—are designed to prevent the country from spiralling out of control like their neighbors. Scotland is recording 188.3 cases per 100,000, less than half the rate of England over the past seven days, according to government figures.

Meanwhile, Johnson has been under intense pressure for prevaricating while cases in England have seen spike upon spike upon spike. That may come to an end on Monday, as the prime minister is due to address the nation and he’s warned that measures are bound to tighten. It’s not clear, however, exactly what the new action will be.

Asked what was taking him so long to do something, Johnson said: “What we have been waiting for is to see the impact of the tier four measures on the virus and it is a bit unclear, still, at the moment. But if you look at the numbers, there is no question that we are going to have to take tougher measures and we will be announcing those in due course.”

Health Secretary Matt Hancock has admitted that the rules that had worked since spring’s lockdown are “no longer strong enough.”

Even more worryingly, though, is Hancock’s belief that the new British variant may not even be the biggest threat facing an already engulfed nation. He said Monday that he’s “incredibly worried” about a South African variant that has been deemed even more transmissible than the British one—and two cases of it have been confirmed in Britain.

Hancock told the BBC on Monday: “This is a very, very significant problem... even more of a problem than the U.K. new variant.”

One reason for that concern may be that British experts have openly queried whether the current vaccines will work on the South African mutant. John Bell, a University of Oxford professor and government vaccine adviser, has said there’s a “big question mark” as to whether the existing vaccines will work on the South African variant.

It’s clear that Britain is in a bad situation—what’s much less clear is if this is as bad as it will get, if new measures will be enough to control the virus mutant, and what happens if an even worse one takes hold.
 
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DIY-HP-LED

Well-Known Member
The new variant of covid is estimated to be 50% to 70% more infectious than the existing strains that means a minimum of four times as many deaths, in America that could mean 10,000 to 20,000 deaths a day, assuming good medical treatment and hardly anybody would be getting it at that point. If people are not treated the case mortality rate could go from 2.7% in Canada to 10%. In America they have a case mortality rate of 1.7%, but the level of care in Canada and America are the same, so there might be something wrong with the US numbers.

If the number of cases increases by 4 times, the death rate will increase by 4 times at least with overwhelmed hospitals. That could mean 50,000 to 100,000 people dying a day in the USA.
 

Fogdog

Well-Known Member
We don't like no big guberment and we don't like no stink'n masks, FREEDOM! Yep if this hits North America they will be breaking up anti mask rallies with flamethrowers. Not just in the states either, this UK strain alone might lead to four times the deaths and hospitalizations, hospitals are near capacity and exceeding it in many places. If the new SA strain is vaccine resistant and just as contagious we are fucked, with overloaded hospitals, exhausted staffs and skyrocketing death rates. A large percentage of the 20% of people who normally would end up in hospital would probably die, mortality could be as high as 10% in the untreated.

Once these strains are let loose in the USA it will be a nightmare and not much better in Canada, if the SA variant is vaccine resistant it will be a catastrophe of mass death. There will be very little tolerance of anti maskers and "fakenews" types, things will get very ugly very quickly for them, if the threat level increases dramatically. This is gonna end up as a race of vaccination rates against new variant infection rates. We had better hope the new SA variant if not resistant to the existing vaccines or things could get ugly real fucking fast. If the vaccines won't work with the new strain, neither will the immunity of those who were infected with older strains of covid.
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Britain’s Mutant Coronavirus Strain Has Swamped the Nation, But a Worse Variant Has Already Arrived

GOING UNDER
The daily rate of cases has more than tripled in little over a month and the measures that worked last year are simply not enough this time round.


EDINBURGH, Scotland—It’s only been a few weeks since people in Britain were planning a relatively normal Christmas time with their families thanks to relaxed pandemic rules. Now, with the mutant coronavirus variant fuelling a near-vertical spike in new daily cases, huge parts of the country are starting the new year by being slammed back into the harshest of lockdowns.

The speed of the turnaround has been astonishing and terrifying. At the end of November, following a nationwide lockdown in England, Britain’s case numbers had declined to around 13,000 a day. Now the country has recorded more than 50,000 cases for six days in a row.

By way of comparison, England has recorded 476.9 cases per 100,000 people in the past week—a rate nearly five times worse than California, the worst-affected U.S. state, which, according to the U.S. Centers for Disease Control and Prevention, is recording 98.8 cases per 100,000. The message to the world appears to be clear—the new variant spreads faster, and, without strict preventative measures, this will happen to you too.

View attachment 4786428

Britain’s surge comes despite the planned Christmas relaxation being scrapped, schools closing down for Christmas, and the biggest city, London, being in the top-tier of lockdown for two weeks. Experts have been warning for weeks that the new variant spreads so quickly that rules that may have been worked last year are no longer enough. Political leaders are now scrambling to find how to knock it back, or face catastrophe.

Scotland has gone first. Its devolved nationalist government had already closed the border to England after Prime Minister Boris Johnson confirmed that the new variant was running wild down south. On Monday, Scotland’s first minister, Nicola Sturgeon, announced a lockdown every bit as strict as the one in spring. Her message—stay at home, and keep your kids out of school, or we’ll end up as screwed as England.

Sturgeon has estimated that Scotland is now about four weeks behind England’s surge, but the new rules—which force Scots by law not to leave their homes but for a few essential purposes—are designed to prevent the country from spiralling out of control like their neighbors. Scotland is recording 188.3 cases per 100,000, less than half the rate of England over the past seven days, according to government figures.

Meanwhile, Johnson has been under intense pressure for prevaricating while cases in England have seen spike upon spike upon spike. That may come to an end on Monday, as the prime minister is due to address the nation and he’s warned that measures are bound to tighten. It’s not clear, however, exactly what the new action will be.

Asked what was taking him so long to do something, Johnson said: “What we have been waiting for is to see the impact of the tier four measures on the virus and it is a bit unclear, still, at the moment. But if you look at the numbers, there is no question that we are going to have to take tougher measures and we will be announcing those in due course.”

Health Secretary Matt Hancock has admitted that the rules that had worked since spring’s lockdown are “no longer strong enough.”

Even more worryingly, though, is Hancock’s belief that the new British variant may not even be the biggest threat facing an already engulfed nation. He said Monday that he’s “incredibly worried” about a South African variant that has been deemed even more transmissible than the British one—and two cases of it have been confirmed in Britain.

Hancock told the BBC on Monday: “This is a very, very significant problem... even more of a problem than the U.K. new variant.”

One reason for that concern may be that British experts have openly queried whether the current vaccines will work on the South African mutant. John Bell, a University of Oxford professor and government vaccine adviser, has said there’s a “big question mark” as to whether the existing vaccines will work on the South African variant.

It’s clear that Britain is in a bad situation—what’s much less clear is if this is as bad as it will get, if new measures will be enough to control the virus mutant, and what happens if an even worse one takes hold.
It's already here. We don't monitor virus strains in the US but somebody has checked and found it present in the US including LA area. Some speculate that the surge seen in SoCal is due to this strain. It's like adding gasoline to kerosene and the epidemic is going to swamp hospitals across the US. I wish I could say I was surprised.

Given the politicization of this disease in the US, I don't see anything stopping it until June at the earliest, when we might finally get enough people vaccinated to protect those who won't or can't be vaccinated. Another mutation is on the way, I'm sure of it.
 
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CunningCanuk

Well-Known Member
The new variant of covid is estimated to be 50% to 70% more infectious than the existing strains that means a minimum of four times as many deaths, in America that could mean 10,000 to 20,000 deaths a day, assuming good medical treatment and hardly anybody would be getting it at that point. If people are not treated the case mortality rate could go from 2.7% in Canada to 10%. In America they have a case mortality rate of 1.7%, but the level of care in Canada and America are the same, so there might be something wrong with the US numbers.

If the number of cases increases by 4 times, the death rate will increase by 4 times at least with overwhelmed hospitals. That could mean 50,000 to 100,000 people dying a day in the USA.
Yeah, we are in the same boat in Canada and for many of the same reasons.
 

DIY-HP-LED

Well-Known Member
Yeah, we are in the same boat in Canada and for many of the same reasons.
They better get rolling on vaccinations here ASAP, we are way down on the list of industrialized countries in terms of shots in arms. I think it might be wise to go with a single shot until supplies come online, the risk is negligible and the benefits enormous, healthcare and the vulnerable should still be first inline for the second round. What is happening in the UK is a headlong panic by the government and it's got me wondering about the SA variant. If this little monster is vaccine resistant we are in a world of hurt and death, I don't think it is though, at least I hope it's not. The new UK variant (the one the vaccine works on) that is from 50 to 70% more contagious will break the medical systems here and in America.

If the new SA variant is resistant to vaccines it should be reinfecting people who had the earlier covid strain infections. We should be seeing people who had covid before coming down with it again, perhaps with mild or asymptomatic cases. These spike protein antibodies are the primary way we fight this virus, but there are other antibodies that the body uses too.

If we have the supplies of vaccines (we don't) it should be a 24/7 effort. There should be one trained person giving shots and two people training to do it with them and giving shots too, until they can give them on their own.
 

DIY-HP-LED

Well-Known Member
Yeah, we are in the same boat in Canada and for many of the same reasons.
I think we need to change how we deal with pandemics by changing public health laws and perhaps the constitution. Pandemic responses have to be national efforts, countries have borders and can control entry and exit, provinces can restrict movement but not by much. National mask mandates and lockdowns are required to control spread of pandemics, piecemeal approaches don't work. Once a pandemic emergency is declared the feds need to take charge of some aspects of public health, otherwise it's public health as usual and a provincial matter. The federal government needs the authority to order masks, lockdowns and perhaps even vaccines, they might even consider locking people up and truly stupid large life changing fines for non compliance.

I've seen video of people having to leave a plane because a couple of people didn't want to wear masks. Wrong approach, warn once then taze, cuffs and a bag over their head while they are dragged off the plane ASAP, not zero tolerance, intolerance. These people are antisocial assholes with no point whatsoever, fuck them and fine them bigly, thousands of dollars and ban them from flying for a year of two minimum. I'm sick of these selfish antisocial assholes being handled with velvet gloves, I don't care if they believe bullshit either.
 

DIY-HP-LED

Well-Known Member
Turns out he's a Qtard.


A mental case, took a gun to work twice apparently, potential mass or workplace killer. He's not exactly off the hook, there might be other charges, but he is mental case so they might go easy. How much is a dose of the Pfizer vaccine worth? There were over 500 doses destroyed @$15/dose, or about $8K he should have to pay in restitution. If he goes to jail they might vaccinate him! :lol:
 

hanimmal

Well-Known Member
Turns out he's a Qtard.


My wish list data set on all these crazies gets another nut's entire internet history added to it.
 

DIY-HP-LED

Well-Known Member

How Eight Covid-19 Vaccines Work
Researchers are testing 64 coronavirus vaccines in clinical trials on humans. Here are explanations about how eight of the leading vaccines work.

Messenger RNA Vaccines

Comirnaty

How the Pfizer-BioNTech Vaccine Works
The vaccine, known as Comirnaty, has been approved or authorized for emergency use in several countries, including the United States. Clinical trials showed the vaccine has an efficacy of 95 percent.

mRNA-1273

How Moderna’s Vaccine Works
The vaccine, known as mRNA-1273, has been approved in Canada and authorized for emergency use in the United States. Clinical trials showed the vaccine has an efficacy of 94.5 percent.


Adenovirus-Based Vaccines

AZD1222

How the Oxford-AstraZeneca Vaccine Works
The vaccine, known as AZD1222 or Covishield, is authorized for emergency use in Britain, India and Argentina. Clinical trials showed the vaccine has an efficacy of approximately 70 percent, depending on dosage.

Ad26.COV2.S

How the Johnson & Johnson Vaccine Works
The vaccine, called Ad26.COV2.S, is in Phase 3 trials and has not been authorized by any country. Trial results are expected in January.


Protein-Based Vaccines

NVX-CoV2373
nanoparticle

How the Novavax Vaccine Works
The vaccine, known as NVX-CoV2373, is in Phase 3 trials. The vaccine has not been authorized by any country.


Inactivated Coronavirus Vaccines

CoronaVac

How the Sinovac Vaccine Works
阅读简体中文版 · 閱讀繁體中文版
The vaccine, known as CoronaVac, is approved in China and authorized for emergency use in Bahrain and the United Arab Emirates. Turkey announced the vaccine has an efficacy of 91 percent, and full results from Phase 3 trials are expected in January.


BBIBP-CorV

How the Sinopharm Vaccine Works
The vaccine, known as BBIBP-CorV, is authorized for limited use in China. Sinopharm says the vaccine has an efficacy rate of 79.34 percent.

Covaxin

New · How Bharat Biotech’s Vaccine Works
The vaccine, known as Covaxin, is authorized for emergency use in India, despite a lack of published Phase 3 trial results. The vaccine’s efficacy is not yet known.

See the Coronavirus Vaccine Tracker for the status of other vaccines in development.
 

waterproof808

Well-Known Member
I got the pfizer vax this morning. So far so good. I own some shares in pfizer and I like that they were not part of trumps operation warp speed so I am glad it is what was being offered to me locally.
 
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