here's some interesting info on DMT: from wikipedia
DMT is generally not active orally unless it is combined with a monoamine oxidase inhibitor (MAOI), such as harmaline. Without a MAOI, the body quickly metabolizes orally-administered DMT, and it therefore has no hallucinogenic effect unless the dose exceeds monoamine oxidase's metabolic capacity (very rare). Other means of ingestion such as smoking or injecting the drug can produce powerful hallucinations and entheogenic activity for a short time (usually less than half an hour), as the DMT reaches the brain before it can be metabolised by the body's natural monoamine oxidase. Taking a MAOI prior to smoking or injecting DMT will greatly prolong and potentiate the effects of DMT.
I was wondering if taking 5-HTP before insufflating 5-MeO-DMT would prolong/potentiate it's effect in the same way that taking an MAOI prior to smoking/injecting DMT prolongs its effects. I don't intend to take the 5-MeO-DMT orally, as I do not have access to an MAOI in order to make it active through this route of admin. I take 5-HTP often, and I know it's a totally different creature than any MAOI, so my thought is this probably won't work. Any thoughts/opinions openly welcomed.